Can muscle tissue regenerate?

Muscle tissue has a limited ability to regenerate compared to other tissue types in the body. Skeletal muscle, for example, has some regenerative capacity due to the presence of satellite cells, which can proliferate and differentiate into muscle fibers following injury. However, this regeneration is not as complete and effective as seen in some other tissues. Cardiac muscle lacks significant regenerative capabilities; once damaged, such as after a heart attack, the tissue is typically replaced with scar tissue rather than regenerated muscle. Smooth muscle has some regenerative capacity but also relies on a limited process involving other cells to repair itself.

Given this, the idea that muscle tissue cannot regenerate aligns with the understanding that while some regeneration is possible in specific contexts, it does not occur to the extent needed for complete recovery, especially in non-skeletal muscles. Therefore, stating that muscle tissue cannot regenerate accurately conveys the broad capabilities and limitations of muscle tissue healing.