Which stage of wound healing involves the formation of new tissue?

The stage of wound healing that involves the formation of new tissue is the proliferation phase. During this phase, which typically occurs about 3 to 21 days after injury, new tissue is created to replace the damaged tissue. This process includes angiogenesis (formation of new blood vessels), collagen deposition, and the formation of granulation tissue, which provides a foundation for further tissue remodeling.

In the proliferation phase, fibroblasts play a crucial role as they synthesize collagen and other extracellular matrix components essential for the wound healing process. Additionally, epithelial cells migrate across the wound bed, facilitating re-epithelialization, which is vital for closing the wound.

Understanding this phase is important for wound care specialists, as effective treatment strategies can support and enhance the proliferation of new tissue, thereby promoting quicker healing and reducing complications.